Amyloid

Calcium waves could provide Alzheimer's insights

( astrocytes in the brain’s cortex do more than provide support to neurons )

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New insights on what causes Alzheimer's disease could arise from a recent discovery made by bioengineers from the University of California, San Diego. The finding concerns the infamous amyloid beta peptides (Aβ)—fragments of which form plaques thought to play a role in Alzheimer's disease. The bioengineers found that amyloid beta peptides (Aβ) spontaneously trigger calcium waves in purified cultures of astrocyte cells extracted from the cortex region of rat brains and grown in the lab. These calcium waves could be relevant for understanding the origin of Alzheimer's disease. The accumulation of Amyloid beta fragments and sustained disruption of the calcium balance within cells are leading hypotheses for what causes Alzheimer's disease. To get more: http://www.physorg.com