Neuromelanin in the substantial nigra and Alzheimer

Donate Online Now

The neuromelanins recognized here are present throughout the human brain and accumulate over a lifetime. Reduced neuronal content of neuromelanin in substantia nigra has been reported in patients with Parkinson's disease, Alzheimer's disease, and Rett syndrome. Their production and accumulation in putamen, premotor cortex, cerebellum, and substantia nigra during aging appear to be an important physiological process that serves both to remove toxic quinones and to bind and immobilize toxic metals. Because they have no turnover, neuromelanins constitute an effective and stable system for immobilizing/detoxifying the reactive/toxic metals in human body over its life span. Because substantial amounts of neuromelanins are found in all major brain regions, their detoxifying role is relevant throughout the human brain, and because neuromelanin accumulation takes place over the entire life span, the neuromelanin pigments contains the story of one's life exposure to several endogenous and environmental metals. http://www.pnas.org/content/105/45

Brain link to mother’s high fat diet and offspring’s obesity

A high fat diet during pregnancy may bring about changes in the offsring’s brain that makes them more prone to over-eating and obesity throughout their lives, according to a new rat study that may help explain the rise in childhood obesity. ...http://www.nutraingredients.com

Беларусь ТВ

Posted YVN

Weather Forecast