Tuesday, November 04, 2008

Fruit and vegetable diet is beneficial for Alzheimer’s prevention
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Early in 1997, while working at the University of Illinois at Chicago, our group published a paper in Science describing the cancer chemopreventive potential of resveratrol. This discovery was the result of an ongoing program project supported by the National Cancer Institute in which the primary goal is the discovery and characterization of the natural product inhibitors of carcinogenesis. The compound was isolated from a nonedible legume originally obtained in Peru; the activity leading to the discovery was inhibition of cyclooxygenase. Resveratrol is a structurally simplistic molecule, a stilbene, that does not generally inspire chemists or phytochemists. The chemical structure has been known for decades. Grapes are a valuable source of numerous phytonutrients, including the intensively studied constituent, resveratrol. A question worth addressing is the potential of dietary grape consumption to positively modulate human health. Many studies have suggested cardiovascular benefits, and some work has indicated cancer chemopreventive activity. Data are particularly compelling in the area of skin cancer prevention. With financial support provided by the California Table Grape Commission, novel and exciting preliminary data are emerging from independent research suggesting beneficial activity against other less prevalent but devastating illnesses, such as Alzheimer’s disease and urinary bladder dysfunction. It is further suggested that some of the copious amounts of data obtained with resveratrol may be relevant to grape consumption, especially responses that can be mediated by low concentrations of the substance. Whether future specific health claims will be sought from or allowed by regulatory authorities is not known, but based on existing data, it is clear that grapes should be considered an integral component of fruit and vegetable enriched diets that are recommended by health authorities and widely accepted as beneficial for human health and disease prevention. J. Agric. Food Chem., 56 (16), 6777–6784, 2008

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Pepsi stays dairy-free despite yoghurt drink launch

Pepsi says that the Asian launch of a yoghurt-flavoured soft drink does not reflect a wider-company focus on harnessing the potential nutrition benefits of dairy beverages, despite a growing number of product launches across Europe. ...http://www.nutraingredients.com

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