A common disease mechanism with Alzheimers
( Down syndrome, artery-clogging cardiovascular disease )
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Down syndrome, artery-clogging cardiovascular disease appear to share a common disease mechanism with Alzheimer's disease, says a new research.
Principal investigator Huntington Potter and colleagues at the Florida Alzheimer's Disease Research Center, USF Health Byrd Alzheimer's Institute, made the link after studying mice and humans cell cultures modelling Alzheimer's disease.
Antoneta Granic and team in their study "Alzheimer Ab Peptide Induces Chromosome Mis-segregation and Aneuploidy, including Trisomy 21; Requirement for Tau and APP," published in Molecular Biology of the Cell, provided the mechanism behind previous work by Potter's laboratory showing that all Alzheimer's disease patients harbour some cells with three copies of chromosome 21, known as trisomy 21, a characteristic shared by all the cells in people with the birth defect Down syndrome. ... Full story: http://www.andhranews.net/Technology/2010/January/16-Scientists-Alzheimer-50813.asp
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Down syndrome, artery-clogging cardiovascular disease appear to share a common disease mechanism with Alzheimer's disease, says a new research.
Principal investigator Huntington Potter and colleagues at the Florida Alzheimer's Disease Research Center, USF Health Byrd Alzheimer's Institute, made the link after studying mice and humans cell cultures modelling Alzheimer's disease.
Antoneta Granic and team in their study "Alzheimer Ab Peptide Induces Chromosome Mis-segregation and Aneuploidy, including Trisomy 21; Requirement for Tau and APP," published in Molecular Biology of the Cell, provided the mechanism behind previous work by Potter's laboratory showing that all Alzheimer's disease patients harbour some cells with three copies of chromosome 21, known as trisomy 21, a characteristic shared by all the cells in people with the birth defect Down syndrome. ... Full story: http://www.andhranews.net/Technology/2010/January/16-Scientists-Alzheimer-50813.asp
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