Midlife estrogen exposures and Alzheimer risk

Please Help Support Alzheimer's Research Today!
You r Alzhei me r's do na tion will help billi ons liv e with out it. Donate on line now
Estrogen-containing hormone therapy initiated during late postmenopause does not improve episodic memory (an important early symptom of Alzheimer's disease), and it increases dementia risk. Cognitive consequences of exogenous estrogen exposures during midlife are less certain. Observational evidence implies that use of hormone therapy at a younger age close to the time of menopause may reduce risk of Alzheimer's disease later in life. However, there are concerns that observational findings may be systematically biased. Partial insight on this critical issue may be gleaned from results of ongoing clinical trials involving midlife postmenopausal women (Early versus Late Intervention Trial with Estrogen; Kronos Early Estrogen Prevention Study). The effects of exogenous midlife estrogen exposures and Alzheimer risk can also be approached through better animal models, through carefully designed cohort studies, and through use of surrogate outcomes in randomized controlled trials in midlife women. Selective estrogen receptor modulators have the potential to affect cognitive outcomes and also merit additional study. ... Semin Reprod Med. 2009 May;27(3):283-93

Dairy probiotic dominance not threatened by diversification

The probiotic dairy market is not yet under threat from developments of the use of similar strains in vegetable and soy-based functional products, though the industry is bracing for challenges ahead in educating consumers on their use. ...http://www.nutraingredients.com