Sunday, July 01, 2007


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The launch of Colostrinin


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ReGen and Metagenics are preparing for the launch of Colostrinin:
Colostrinin is a trademarked complex derived from ovine and bovine colostrum (the first milk produced by a mammal after giving birth). In addition to launching Colostirin itself as a nutraceutical, the company is also developing a pharmaceutical preparation based on the peptides within it, for the treatment of Alheimer's disease.

Pre-clinical and human clinical data on Colostrin's role age-related cognitive decline:
One aspect was the reduced production of intracellular reactive oxygen species (ROS), which increase with old age and are associated with tissue and metabolic damage. The company has also looked into the prevention of the aggregation of beta-amyloid, the protein associated with Alzheimer's disease, and its neurotoxicity. Clinical trials involving 150 human subjects with mild to moderate Alzheimer's disease have shown it to have beneficial effects on cognitive and functional performance. ReGen has also conducted animal studies to establish that Colostrinin is well-tolerated at daily doses up to 100 times that recommended for humans, over a prolonged period. Moreover, data has indicated that the nutraceutical given in the drinking water could increase the lifespan of mice prone to premature ageing by around 30 per cent.


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