Omega-3 fatty acids may interfere with the development of Alzheimer's .
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Alzheimer's disease, the most common form of dementia, gradually destroys a person's memory and ability to learn, communicate, and carry out daily activities. According to the American Health Assistance Foundation, more than 4.5 million people in the United States live with the disease and more than 26 million people are affected worldwide.
Supplements of omega-3 fatty acids may help combat the depression and agitation symptoms associated with Alzheimer's disease, says a new clinical trial.
The new study, led by Yvonne Freund-Levi from Sweden's Karolinska Institutet, divided the participants to receive omega-3 supplements (docosahexaenoic acid (DHA) 1.7 g and eicosapentaenoic acid (EPA) 0.6 g) or placebo for six months. After this initial six month period, all participants received the omega-3 supplements for six further months.
The researchers called for larger studies on individuals with more pronounced neuropsychiatric symptoms to confirm these results before any general recommendations can be made. "Supplementation with omega-3 in patients with mild to moderate AD did not result in marked effects on neuropsychiatric symptoms except for possible positive effects on depressive symptoms in non-APOE4 carriers and agitation symptoms in APOE4 carriers," concluded the researchers.
Although the mechanism of Alzheimer's is not clear, more support is gathering for the build-up of plaque from beta-amyloid deposits. The deposits are associated with an increase in brain cell damage and death from oxidative stress. But how omega-3 fatty acids may interfere with the development of Alzheimer's disease is not clear, said the authors, but suggested that the benefits may be linked to the fish oil's anti-inflammatory effects, although no such effects were observed in this study.
More omega-3, less omega-6 better for prostate
Increasing omega-3, and decreasing omega-6 could reduce the risk of prostate cancer risk in individuals with a genetic predisposition to cancer, suggests an animal study.
Donate Online Now
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Alzheimer's disease, the most common form of dementia, gradually destroys a person's memory and ability to learn, communicate, and carry out daily activities. According to the American Health Assistance Foundation, more than 4.5 million people in the United States live with the disease and more than 26 million people are affected worldwide.
Supplements of omega-3 fatty acids may help combat the depression and agitation symptoms associated with Alzheimer's disease, says a new clinical trial.
The new study, led by Yvonne Freund-Levi from Sweden's Karolinska Institutet, divided the participants to receive omega-3 supplements (docosahexaenoic acid (DHA) 1.7 g and eicosapentaenoic acid (EPA) 0.6 g) or placebo for six months. After this initial six month period, all participants received the omega-3 supplements for six further months.
The researchers called for larger studies on individuals with more pronounced neuropsychiatric symptoms to confirm these results before any general recommendations can be made. "Supplementation with omega-3 in patients with mild to moderate AD did not result in marked effects on neuropsychiatric symptoms except for possible positive effects on depressive symptoms in non-APOE4 carriers and agitation symptoms in APOE4 carriers," concluded the researchers.
Although the mechanism of Alzheimer's is not clear, more support is gathering for the build-up of plaque from beta-amyloid deposits. The deposits are associated with an increase in brain cell damage and death from oxidative stress. But how omega-3 fatty acids may interfere with the development of Alzheimer's disease is not clear, said the authors, but suggested that the benefits may be linked to the fish oil's anti-inflammatory effects, although no such effects were observed in this study.
More omega-3, less omega-6 better for prostate
Increasing omega-3, and decreasing omega-6 could reduce the risk of prostate cancer risk in individuals with a genetic predisposition to cancer, suggests an animal study.
posted by Valery Yermalitsky at
7:58 AM
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