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Behavioral and psychological symptoms of dementia represent a major challenge in the care of older adults with Alzheimer disease. In a study published in the May 10 issue of the Journal of the American Medical Association, researchers from the Indiana University Center for Aging Research and the Regenstrief Institute, Inc. report improved quality and outcomes of care for Alzheimer disease by restructuring the primary care practice environment to emphasize a team approach to care. More than 90 percent of patients with Alzheimer disease will experience behavioral and psychological symptoms of dementia at some point during the course of the illness. Leaving these symptoms of dementia untreated has been associated with nursing home placement, poor management of other health problems, high health-care costs and caregiver burn out. For these reasons, the team approach to care emphasized management of these important symptoms. “We wanted to build a treatment infrastructure within primary care, where most people with Alzheimer disease get their health care. We asked, what would happen if we put together an interdisciplinary team led by a primary care physician and an advanced practice nurse who served as the care manager working with the patient and the caregiver giving them access to resources, providing education, and helping them navigate the health-care system,” said Christopher Callahan, M.D., the study's principal investigator.

Biotechnology Limited (Nasdaq: PRAN, ASX: PBT), today announced that it
plans to move forward with a Phase IIa clinical trial of its proprietary
lead compound, PBT2, in patients with Alzheimer's disease. http://www.medicalnewstoday.com/medicalnews.php?newsid=43289