Alzheimer's Cognitive Decline by New Treatment
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Unprecedented results using a new way to treat Alzheimer's Disease(AD) were published this week in the neurology section of the peer-reviewed journal, Medscape General Medicine. The article presents the results of a six-month, open-label, uncontrolled pilot study in which 15 patients with Alzheimer's ranging in severity from mild to severe received weekly perispinal injections of etanercept, a medication designed to reduce excess levels of tumor necrosis factor (TNF). TNF is a molecule which initiates and amplifies the inflammatory response in the brain and other organ systems. "There is an enormous unmet medical need in Alzheimer's disease, an incurable, terminal and devastating affliction for the patient, as well as for families and society in general," stated Dr. Cohen. "We should take these findings very seriously and confirm them in broader trials initiated immediately." The full-study is available at www.medscape.com

U of T find could lead to treatment for Alzheimer'sNews@UofT - Toronto,Ontario,Canada... newly found protein blocks the creation of nerve toxins in Alzheimer's, a disease ... an increase in levels of the neurotoxin, called Abeta or beta-amyloid peptide ...
Korean scientists find new trigger for Alzheimer'sKorea Herald (subscription) - Seoul,South Korea... which reside at the tip of the amyloid precursor-like ... indirubin-3, an inhibitor against GSK3-beta, will help ... the number of dying neurons in Alzheimer's patients ...

Researchers from Georgetown University Medical Center's Memory Disorders Program are directing the first U.S. study to determine whether huperzine A, derived from the Chinese club moss plant Huperzia serrata, improves cognitive function in people with Alzheimer's disease (AD). http://www.medicalnewstoday.com/medicalnews.php?newsid=42330