n–3 Fatty acids and health:
DELAYED PASSING OF THE FRAIL?

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Two are prospective cohort studies based on n–3 FA biomarkers (as opposed to dietary intake estimates), and the third is a randomized controlled, dose-response study. Attesting to the pleiotrophic effects of the n–3 FAs, the endpoints in these studies ran the gamut from all-cause mortality and cognitive decline in the former 2 studies to mood and mental health in the latter study. In short, the story they tell is this: low in vivo concentrations of EPA (eicosapentaenoic acid) or DHA (docosahexaenoic acid) predict an increased risk of death in frail, hospitalized octogenarians from Norway and an accelerated cognitive decline in free-living septuagenarians from France. Hence, the ability of markers of n–3 FA biostatus continue to provide potentially relevant prognostic information for clinically important endpoints. On the other hand, intervention with EPA+DHA in the healthy elderly had no effect on mental well-being. Together, these findings suggest that dietary habits that include higher versus lower intakes of long-chain n–3 FAs may bring certain health benefits that short-term supplementation cannot provide. Supplementation can, of course, affect other factors (eg, serum triglyceride concentrations, susceptibility to arrhythmic events, and platelet aggregation, all with potential clinical relevance. American Journal of Clinical Nutrition, Vol. 88, No. 3, 595-596, September 2008

Oily fish may boost prostate cancer survival rate

An increased intake of fish and omega-3-rich seafood may improve prostate cancer survival by 38 per cent, according to a new study. ...http://www.nutraingredients.com

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