Vitamin E delays the progression of moderately severe Alzheimer's
An increased intake of vitamin E supplements may improve the survival of people suffering from Alzheimer's disease, researchers report. Regular supplementation with vitamin E was associated with 26 per cent lower mortality rates, according to data obtained from 847 people with Alzheimer's disease presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago.
"Vitamin E has previously been shown to delay the progression of moderately severe Alzheimer's disease. Now, we've been able to show that vitamin E appears to increase the survival time of Alzheimer's patients as well," said lead author Valory Pavlik, PhD., from Baylor College of Medicine. "This is particularly important because recent studies in heart disease patients have questioned whether vitamin E is beneficial for survival."
Talking to NutraIngredients.com, Dr. Pavlik indicated that the results of the study, a long-term follow-up of an Alzheimer's disease patient cohort, are in-line with a randomised, placebo-controlled trial reported in the New England Journal of Medicine (1997, Vol. 336, pp. 1216-22), which showed a beneficial effect of vitamin E (2000 IU total per day) in Alzheimer patients. "We are not aware of any other studies that have examined vitamin E just in relation to all-cause mortality in Alzheimer's disease patients," said Dr. Pavlik. In addition, the study found vitamin E plus a cholinesterase inhibitor may be more beneficial than taking either agent alone. "Our findings show that people who took a cholinesterase inhibitor without vitamin E did not have a survival benefit," said Pavlik. "More research needs to be done to determine why this may be the case."
Alzheimer's disease (AD) is the most common form of dementia and currently affects over 13 million people worldwide. The direct and indirect cost of Alzheimer care is over $100 bn (€ 81 bn) in the US, while direct costs in the UK are estimated at £15 bn (€ 22 bn).
"Vitamin E has previously been shown to delay the progression of moderately severe Alzheimer's disease. Now, we've been able to show that vitamin E appears to increase the survival time of Alzheimer's patients as well," said lead author Valory Pavlik, PhD., from Baylor College of Medicine. "This is particularly important because recent studies in heart disease patients have questioned whether vitamin E is beneficial for survival."
Talking to NutraIngredients.com, Dr. Pavlik indicated that the results of the study, a long-term follow-up of an Alzheimer's disease patient cohort, are in-line with a randomised, placebo-controlled trial reported in the New England Journal of Medicine (1997, Vol. 336, pp. 1216-22), which showed a beneficial effect of vitamin E (2000 IU total per day) in Alzheimer patients. "We are not aware of any other studies that have examined vitamin E just in relation to all-cause mortality in Alzheimer's disease patients," said Dr. Pavlik. In addition, the study found vitamin E plus a cholinesterase inhibitor may be more beneficial than taking either agent alone. "Our findings show that people who took a cholinesterase inhibitor without vitamin E did not have a survival benefit," said Pavlik. "More research needs to be done to determine why this may be the case."
Alzheimer's disease (AD) is the most common form of dementia and currently affects over 13 million people worldwide. The direct and indirect cost of Alzheimer care is over $100 bn (€ 81 bn) in the US, while direct costs in the UK are estimated at £15 bn (€ 22 bn).
Unilever has withdrawn its soy juice - AdeZ - in the UK, after little more than 18 months on market after consumers failed to connect with its health messaging.http://www.nutraingredients.com
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posted by Valery Yermalitsky at
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