Alzheimer's and Omega-3 Fatty Acids

.
Alzheimer's Donation
Donate Online Now

.

This is a good-fat-bad-fat stories of the holiday. Scientists examined the lipid regulation of an ApoE/low-density lipoprotein receptor, the neuronal sortilin-related receptor (SorLA or LR11). LR11 can reduce beta-amyloid production by guiding APP in recycling Golgi and early endosome pathways, thus trafficking APP away from beta- and beta-secretase. Polymorphisms that reduce LR11 expression also have been associated with increased Alzheimer's disease (AD) risk.

The authors report that the essential omega-3 fatty acid docosahexaenoic acid (DHA) increases LR11 in a neuronal cell line and in primary neurons. DHA also increased LR11 in membrane fractions from aged normal mice and in transgenic mice that overexpressed APP. Dietary fish oil had similar effects in rats with increased AD risk. The authors suggest that this regulation may contribute to the reduced AD risk with increased fish consumption. http://www.medicalnewstoday.com

Immunity and digestion drives kids nutrition
Omega-3 added to products will remain a niche market in kids' foods for the following year unless it is really pushed by a large food company, a report has said.

osted YVN