Exelon patch is the first to treat Alzheimer's
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The European Commission has approved Exelon patch (rivastigmine transdermal patch), an innovative way to deliver this effective medicine to patients suffering from mild to moderately severe Alzheimer's disease.
Exelon patch is the first and only transdermal treatment for Alzheimer's disease, a degenerative brain disorder affecting 18 million people worldwide and the third leading cause of death behind cardiovascular disease and cancer3. The skin patch is applied oncedaily to the back, chest or upper arm of patients. "Exelon patch represents a therapeutic innovation that is designed specifically to meet the needs of patients, caregivers and physicians involved with this devastating disease," said James Shannon, MD, Global Head of Development at Novartis Pharma AG. "The patch has been shown to increase compliance, reduce side effects, and allow medication to be delivered through the skin into the bloodstream smoothly and continuously over 24 hours, helping to achieve optimal dosing. All these benefits offer the potential for improved outcomes in patients," Shannon said. The European Union approval, coming soon after the US approval in July 2007, was based on results from the international IDEAL (Investigation of Transdermal Exelon in ALzheimer's disease) study, which involved nearly 1,200 patients with mild to moderate Alzheimer's disease1.
The patch showed similar efficacy to the highest doses of Exelon capsules, as well as significant improvement in memory and the ability to perform everyday activities compared to placebo1. In addition, the IDEAL study demonstrated three times fewer reports of gastrointestinal side-effects (nausea and vomiting) with the patch than the oral form of the medication. "The patch is an important new addition to existing oral treatment options since it provides visual reassurance that patients have 'taken' their medicine," said Bruno Dubois, Professor of Neurology at the Hôpital Pitié Salpétrière, Centre de Neuropsychologie, Paris, France. "Just having to apply a patch can help reduce the burden of daily life for people with Alzheimer's disease and their families."
Designed with compliance in mind, the patch was preferred by more than 70% of caregivers as a method of drug delivery because it helped them follow treatment schedules and was easier to use than an oral medicine. "People with Alzheimer's disease and their caregivers welcome every new therapy for the disease," said Mark Wortmann, Executive Director of Alzheimer's Disease International - an umbrella organization of Alzheimer Associations around the world which offer support and advice to people with the disease and their carers. "I am pleased that the patch offers a new approach to treatment." http://www.medicalnewstoday.com
Omega-3 may reduce type-1 diabetes
posted YVN
.
Alzheimer's Donation
Donate Online Now
.
The European Commission has approved Exelon patch (rivastigmine transdermal patch), an innovative way to deliver this effective medicine to patients suffering from mild to moderately severe Alzheimer's disease.
Exelon patch is the first and only transdermal treatment for Alzheimer's disease, a degenerative brain disorder affecting 18 million people worldwide and the third leading cause of death behind cardiovascular disease and cancer3. The skin patch is applied oncedaily to the back, chest or upper arm of patients. "Exelon patch represents a therapeutic innovation that is designed specifically to meet the needs of patients, caregivers and physicians involved with this devastating disease," said James Shannon, MD, Global Head of Development at Novartis Pharma AG. "The patch has been shown to increase compliance, reduce side effects, and allow medication to be delivered through the skin into the bloodstream smoothly and continuously over 24 hours, helping to achieve optimal dosing. All these benefits offer the potential for improved outcomes in patients," Shannon said. The European Union approval, coming soon after the US approval in July 2007, was based on results from the international IDEAL (Investigation of Transdermal Exelon in ALzheimer's disease) study, which involved nearly 1,200 patients with mild to moderate Alzheimer's disease1.
The patch showed similar efficacy to the highest doses of Exelon capsules, as well as significant improvement in memory and the ability to perform everyday activities compared to placebo1. In addition, the IDEAL study demonstrated three times fewer reports of gastrointestinal side-effects (nausea and vomiting) with the patch than the oral form of the medication. "The patch is an important new addition to existing oral treatment options since it provides visual reassurance that patients have 'taken' their medicine," said Bruno Dubois, Professor of Neurology at the Hôpital Pitié Salpétrière, Centre de Neuropsychologie, Paris, France. "Just having to apply a patch can help reduce the burden of daily life for people with Alzheimer's disease and their families."
Designed with compliance in mind, the patch was preferred by more than 70% of caregivers as a method of drug delivery because it helped them follow treatment schedules and was easier to use than an oral medicine. "People with Alzheimer's disease and their caregivers welcome every new therapy for the disease," said Mark Wortmann, Executive Director of Alzheimer's Disease International - an umbrella organization of Alzheimer Associations around the world which offer support and advice to people with the disease and their carers. "I am pleased that the patch offers a new approach to treatment." http://www.medicalnewstoday.com
Omega-3 may reduce type-1 diabetes
An increased intake of omega-3 fatty acids from marine sources may protect children at high risk of type-1 diabetes from developing the disease, suggests new research.
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